Promising Data from CARE PMR Study Presented at AAIC 2025 Highlights Portable MRI as a Game-Changer for Point-of-Care Monitoring

New interim results presented by our partner Hyperfine at the 2025 Alzheimer’s Association International Conference (AAIC) in Toronto are set to transform Alzheimer’s patient monitoring. Data from the CARE PMR study, led by researchers at the Benzinger Lab at Washington University School of Medicine in St. Louis, shows that the Swoop® AI-powered portable MRI system achieved 100% sensitivity in detecting ARIA-E (amyloid-related imaging abnormalities with edema) in Alzheimer’s patients undergoing Lecanemab therapy.

This groundbreaking finding underscores the potential of ultra-low-field MRI as a triage tool for rapid, point-of-care ARIA screening. By bringing advanced brain imaging directly to neurology clinics and infusion centers, the Swoop® system addresses critical barriers to traditional MRI access, such as high costs, scheduling delays, and geographic limitations.

The study, which aligns with FDA-required MRI safety monitoring protocols for amyloid-targeting therapies, demonstrates how portable MRI can significantly

improve monitoring and expand access to care for patients receiving treatments like Lecanemab. This innovation brings high-quality brain imaging closer to patients, ultimately aiming to alleviate the burden on families and facilities and enhance overall access to neurological care.

As Hyperfine’s Chief Medical Officer, Dr. Edmond Knopp, stated, “We are proud to collaborate with leading clinicians and researchers who share our vision of advancing Alzheimer’s care through accessible innovation.

This new era of Alzheimer’s care, with imaging that meets patients where they are, is now within reach.

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